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師資陣容 基礎醫學師資
基礎醫學師資
謝政蓉

基本資料表

姓名

謝政蓉

職稱

教授

E-mail

pipi58871053@yahoo.com.tw

連絡電話

06-2674567 #600

學經歷一覽

學歷

1998/09 -2004/01

國立成功大學醫學院基礎醫學研究所博士

 

1993/09 -1995/06

紐澤西羅格斯州立大學(Rutgers-The State University of New Jersey)       微生物學研究所碩士

 

1988/09-1992/06

私立高雄醫學大學醫學技術系學士

經歷

2018/08-迄今

中華醫事科技大學護理學院院長

 

2016/08-2018/07

2014/08-2015/03

中華醫事科技大學醫學與生命學院院長

 

2012/05-迄今

中華醫事科技大學教授

2007/03-2012/04

中華醫事科技大學護理系副教授

2004/05-2007/02

中華醫事學院護理系副教授

 

1996/02-2004/04

中華醫事學院護理系講師

 

1994/09-1995/06

紐澤西羅格斯州立大學教學助教

 

1992/08-1993/06

中央研究院研究助理

教學與研究領域

微生物學、免疫學、基因治療、腫瘤生物學 細胞生物學

期刊論文一覽

論文名稱

刊物名稱

期刊類別

1.Shih-Yao Chen, I-Ming Jou, Chao-Liang Wu, Po-Ting Wu, Ai-Li Shiau, Hao-Earn Chong, Yu-Ting Lo, Po-Chuan Shen, and Jeng-Long Hsieh. Estrogen and Mechanical Loading-dependent Regulation of Estrogen Receptor-β and Apoptosis in Tendinopathy. (Under revision).

PLOS ONE

SCI

2.Jeng-Long Hsieh , Po-Chuan Shen, Po-Ting Wu, I-Ming Jou, Chao-Liang Wu, Ai-Li Shiau, Chrong-Reen Wang, Hao-Earn Chong, Shu-Han Chuang, Jia-Shiou Peng , Shih-Yao Chen (2017). Knockdown of toll-like receptor 4 signaling pathways ameliorate bone graft rejection in a mouse model of allograft transplantation. 7:46050. doi: 10.1038/srep46050.

Scientific Reports

SCI

3.Fang-Hsin Lee, Po-Chuan Shen, I-Ming Jou, Chung-Yi Li, Jeng-Long Hsieh* (2015). A population-based sixteen-year study on the risk factors of surgical site infection in patients after bone grafting-a cross-sectional study in Taiwan . 94(47): e2034. .

Medicine

SCI

4.Po-Chuan Shen, Ping-Hui Wang, Po-Ting Wu, Kuo-Chen Wu, I-Ming Jou, Jeng-Long Hsieh* (2015). The Estrogen Receptors-β Expression in de Quervain’s Disease. International Journal of Molecular Sciences. 16: 26452-26462.

International Journal of Molecular Sciences,

SCI

5.Jeng-Long Hsieh, Chia-Sing Lu, Chia-Yi Lin, Hsiu-Wen Tsai, Bing-Hua Su, Gia-Shing Shieh, Yu-Chu Su, Che-Hsin Lee, Meng-Ya Chang, Chao-Liang Wu and Ai-Li Shiau (2015). Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer. 22(4): 305-15.

Gene Therapy ,

 

 

 

SCI

6.Chiang-Liang Lin, Wei-Fan Chiang, Chao-Ling Tung, Jeng-Long Hsieh, Hsiao Jenn-Ren, Huang Wen-Tsung, Li-Yia Feng, Chi-Hua Chang, Shyun-Yeu Liu, Chao-Jung Tsao, and Yin-Hsun Feng. (2015). Sprouty2 protein is downregulated in human squamous cell carcinoma of the head and neck and suppresses cell proliferation in vitro. 11(1): 547-554.

Molecular Medicine Reports

 

 

 

SCI

7.CH Lee, ST Lin, JJ Liu, WW Chang, Jeng-Long Hsieh, WK Wang. (2014) Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway. 21(3): 309-16.

Gene Therapy,

SCI

8.Wei-Kuang Wang, Song-Tao Lin, Wen-Wei Chang, Li-Wen Liu, Tom Yu-Tung Li, Chun-Yu Kuo, Jeng-Long Hsieh, Che-Hsin Lee (2014) Hinokitiol induces autophagy in murine breast and colorectal cancer cells. doi: 10.1002/tox.22023.

Environmental toxicology

SCI

9.Ai-Li Shiau Yu-Ting Shen, Jeng-Long Hsieh, Chao-Liang Wu and Che-Hsin Lee. (2014) Scutellaria barbata inhibits angiogenesis through downregulation of HIF-1 α in lung tumor. 29(4): 363-70.

Environmental toxicology

SCI

10.Po-Chuan Shen, Chia-Sing Lu, Ai-Li Shiau, Che-Hsin Lee, I-Ming Jou, Jeng-Long Hsieh* (2013) Lentiviral small hairpin RNA knockdown of macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice. 24(10): 871-82.

Human Gene Therapy,

SCI

11.Jeng-Long Hsieh, Ai-Li Shiau, Che-Hsin Lee, Yang SJ, Bih-O Lee, I-Ming Jou, Chiao-Liang Wu, Chen SH, Po-Chuan Shen (2013) CD8+ T Cell-Induced Expression of Tissue Inhibitor of Metalloproteinses-1 Exacerbated Osteoarthritis. 14(10): 19951-19970.

International Journal of Molecular Sciences,

SCI

12.Che-Hsin Lee, Yu-Hsin Lin, Jeng-Long Hsieh, Man-Chin Chen and Wan-Lin Kuo (2013) A polymer coating applied to Salmonella prevents the binding of Salmonella-specific antibodies. 132(3): 717-25.

International Journal of J Cancer

SCI

13.Jeng-Long Hsieh, Chia-Sing Lu, Chin-Ling Hwang, Gia-Shing Shieh, Bing-Hua Su, Yu-Chu Su, Che-Hsin Lee, Meng-Ya Chang, Chao-Liang Wu and Ai-Li Shiau (2012) Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment. 321(1): 36-44.

Cancer Letters

 

 

 

SCI

14.Che-Hsin Lee, Jeng-Long Hsieh, Chao-Liang Wu, Hui-Chun Hsu, Ai-Li Shiau (2011) B cells are required for tumor-targeting Salmonella in host. 92(6): 1251-60.

Applied Microbiology and Biotechnology

 

SCI

15.Po-Chuan Shen, Chao-Liang Wu, I-Ming Jou, Che-Hsin Lee, Hsin-Yi Juan, Pei-Ju Lee, Shun-Hua Chen, Jeng-Long Hsieh* (2011) T helper cells promote disease progression of osteoarthritis by inducing macrophage inflammatory protein-1. 19(6): 728-736

Osteoarthritis and cartilage

 

 

SCI

16.Che-Hsin Lee, Jeng-Long Hsieh, Chao-Liang Wu, Pei-Yu Hsu, Ai-Li Shiau (2011) T cell augments the antitumor activity of tumor-targeting Salmonella. 90(4): 1381-8

Applied Microbiology and Biotechnology

 

SCI

17.Po-Chuan Shen, Ai-Li Shiau, I-Ming Jou, Che-Hsin Lee, Ming-Hong Tai, Hsin-Yi Juan, Pey-Ru Lin, Guei-Sheung Liu, Chao-Liang Wu and Jeng-Long Hsieh* (2011) Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis. 236(3): 334-340. (SCI, R/C=67/123, Medicine, Research & Experimental)

Experimental Biology and Medicine

 

 

 

SCI

18.Jeng-Long Hsieh, Po-Chuan Shen, Ai-Li Shiau, I-Ming Jou, Che-Hsin Lee, Chrong-Reen Wang, Min-Li Teo, Chao-Liang Wu (2010) Intraarticular Gene Transfer of Thrombospondin-1 Suppresses the Disease Progression of Experimental Osteoarthritis. 28(10): 1300-1306.

Journal of Orthopaedic Research

 

 

SCI

19.Ai-Li Shiau, Min-Li Teo, Shin-Yao Chen, Chrong-Reen Wang, Jeng-Long Hsieh, Meng-Ya Chang, Chih-Jui Chang, Julie Chao, Lee Chao, Chao-Liang Wu, Che-Hsin Lee (2010) Inhibition of experimental lung metastasis by systemic lentiviral delivery of kallistatin. 10: 245-253.

BMC Cancer

 

 

 

SCI

20.Jeng-Long Hsieh, Che-Hsin Lee, Min-Li Teo, Yih-Jyh Lin, Yen-Sung Huang, Chao-Liang Wu and Ai-Li Shiau (2009) Transthyretin Driven Oncolytic Adenovirus Suppressed Tumor Growth in Orthotopic and Ascites Models of Hepatocellular Carcinoma. 100(3): 537-545.

Cancer Science

 

 

SCI

21.Jeng-Long Hsieh, Po-Chuan Shen, Ai-Li Shiau, I-Ming Jou, Che-Hsin Lee, Min-Li Teo, Chrong-Reen Wang, Julie Chao, Lee Chao, and Chao-Liang Wu (2009) Adenovirus-Mediated Kallistatin Gene Transfer Ameliorates Disease Progression in a Rat Model of Osteoarthritis Induced by Anterior Cruciate Ligament Transection. 20(2): 147-158.

Human Gene Therapy

 

 

SCI

22.K-F Hsu, C-L Wu, S-C Huang, Jeng-Long Hsieh, Y-S Huang, Y-F Chen, M-R Shen, W-J Chung, C-Y Chou and A-L Shiau (2008) Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy. 15: 526-34.

Cancer Gene Therapy

 

 

SCI

23.Jeng-Long Hsieh, Chao-Liang Wu, Lia Ming-Derg, Ching-Shan Tsai, Che-Hsin Lee, and Ai-Li Shiau (2003) Gene therapy for bladder cancer using E1B-55 kd-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1-5. (88): 1492-1499.

British Journal of Cancer

 

 

SCI

24.Jeng-Long Hsieh, Chao-Liang Wu, Che-Hsin Lee, and Ai-Li Shiau (2003) Hepatitis B X protein sensitizes hepatocellular carcinoma cells to cytolysis induced byE1B-deleted adenovirus through the disruption of p53 function. (9): 338-345.

Clinical Cancer Research

 

 

SCI

研討會論文一覽

論文名稱

研討會名稱. 國家. 城市

1. The expression and potential roles of Estrogen Receptor-beta in musculoskeletal diseases

The 18th World Congress of

Basic and Clinical Pharmacology Kyoto, Japan. ( 2018/07/01-06)

2.儀器設備更新與教學品質改善之關聯性分析

中華醫事科技大學校務研究研討會暨成果發表會 (2017/12/14)

3. The effect of estrogen receptor-β and tensile stress on tendinopathy. Jeng-Long Hsieh, Po-Chuan Shen, Hao-Earn Chong, Shih-Yao Chen.

The ISER international Conference on Science, Health and Medicine Orlando, USA. ( 2017/08/18-19)

4. Knockdown of toll like receptor 4 signaling pathway ameliorates bone graft rejection in a mouse model of allograft transplantation.

The 22th Annual Meeting of the Japan Society of gene therapy. Tokyo, Japan.(2016/07/28-30)

5.Targeting estrogen receptor-beta has a therapeutic implication for the treatment of de Quervain’s disease.

International Conference and Exhibition on Molecular Medicine and Diagnostics, London, United Kingdom.(2015/08/24-27).

6. A new Oct3/4-activated oncolytic adenovirus mediated by hypoxia exerts enhanced antitumor activity in bladder cancers.

The 21th Annual Congress of the European society of gene and cell therapy. Versailles, Madrid.(2013/10/25-28)

7. Lentiviral shRNA knock-down of Macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice.

The 20th Annual Congress of the European society of gene and cell therapy. Versailles, France. (2012/10/25-29)

8. Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis.

The 19th Annual Congress of the European society of gene and cell therapy. Brighton, United Kingdom.(2011/10/27-30)

9.退化性關節炎只是單純的退化嗎?-有關其發炎機制的探討與基因治療的二、三事。

中華醫事科技大學護理系-國際研討會口頭發表(2011/07/03)

10. Intraarticular gene transfer of thrombospodin-1 suppresses disease progression of experimental osteoarthritis.

The 17th Annual Congress of the European society of gene and cell therapy. Hannover, Germany.(2009/11/20-25)

11. Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transaction

The 16th Annual Congress of the European society of gene and cell therapy. Brugge, Belgium.(2008/11/13-16)

12. Selective targeting of hepatocellular carcinoma with an oncolytic adenovirus regulated transthyretin promoter in orthotopic and ascites tumor models.

The 15th Annual Congress of the European society of gene and cell therapy. Rotterdam, Netherlands.(2007/10/28-31)

13.利用癌溶性腺病毒於肝原位癌與腹水的基因治療

中華醫事科技大學護理系-研究發展研習營口頭論文發表(2007/6/8

14. Tumor targeting of an oncolytic adenovirus regulated by transthyretin promoter on malignant ascites associated with hepatocellular carcinoma.

The 12th Annual Meeting of the Japan Society of gene therapy. Tokyo, Japan.(2006/8/24-26)

研究計劃一覽

計劃名稱

計畫執行起迄

擔任職務

研究計畫類別

1.雌激素受體-β於肌腱病變疾病的角色探討與基因治療(科技部研究計畫105/08/01-106/07/31)

08/01/2016-07/31/2019

三年期研究計畫主持人

MOST 105-2314-B-273 -001-MY3

科技部

2.儀器設備更新與教學品質改善之關聯性分析

01/01/2017-12/31/2017

研究計畫主持人

教育部大學校務研究計畫

3.研究類鐸受體所媒介的myeloid differentiation primary response gene 88依賴性與獨立性訊息傳導路徑在骨移植中扮演的角色

08/01/2013-07/31/2016

三年期研究計畫主持人

NSC 102-2314-B-273-002-MY3

科技部·

4.探討淋巴細胞調控退化性關節炎生成之機轉

08/01/2012-07/31/2013

研究計畫主持人

NSC101-2314-B-273-001-

國科會

5.退化性關節炎的基因治療與抗發炎因子作用機制的探討

08/01/2009-07/31/2012

三年期研究計畫主持人

NSC98-2314-B-273-001-MY3) ·國科會

6. 探討類鐸受體四號對於腫瘤生長之影響

08/01/2010-07/31/2011

二年期研究計畫共同主持人

NSC 99 -2320-B-039 -001 -MY2國科會

7.以腺病毒攜帶抗發炎和抗血管新生因子作退化性關節炎的基因治療

08/01/2008-07/31/2009

研究計畫主持人

NSC 97-2314-B-273 -001 –

國科會

8.以癌溶性病毒作肝原位癌的基因治療(二年期研究計畫主持人

08/01/2006-07/31/2008

二年期研究計畫主持人

NSC 95-2320-B-273-002-MY2國科會

9.利用肝特異性E1B缺失腺病毒作肝腫瘤基因治療

08/01/2005-07/31/2006·

研究計畫主持人

NSC 94-2320-B-273-004-

國科會

產學合作計畫

 

1.關節與肌腱病變之基因治療

08/01/2018-07/31/2019

研究計畫主持人

臺南市立安南醫院

2.探討雌激素受體-α於肌腱病變疾病的角色

01/01/2018-12/31/2018

醫療科技研究計畫共同主持人

成功大學醫學院附設醫院

3.幹細胞應用於肌肉骨骼關節病變之治療(計畫主持人)

05/01/2017-04/30/2018

研究計畫主持人

承洺科技股份有限公司

4.探討雌激素接受器β與狄奎凡氏症(桡骨莖突狹窄性腱鞘炎)病理嚴重程度之相關性

01/01/2015-12/31/2015

醫療科技研究計畫共同主持人

成功大學醫學院附設醫院

5.利用慢病毒攜帶tissue inhibitor of metalloproteinase-1 (TIMP-1)的干擾性RNA(shRNA)作退化性關節炎的基因治療(產學合作研究計畫主持人) ·

06/10/2012-06/09/2013

研究計畫主持人

衛生福利部台南醫院

6.Sorafenib合併化學藥物對頭頸部鱗狀上皮癌細胞的療效研究

01/01/2011-12/31/2011

研究計畫主持人

奇美醫療財團法人奇美醫院

7.類鐸受體四號TLR4作為偵測退化性關節炎的炎症指標

11/01/2010-04/30/2011

研究計畫主持人

明麗骨科診所

榮譽獎項

日期

事件細節

頒獎機構

作者順序

2017

106年科技部補助大專校院獎勵特殊優秀人才獎勵

科技部

第一作者

2016

105年科技部補助大專校院獎勵特殊優秀人才獎勵

科技部

第一作者

2015

104年中華醫事科技大學教學優良教師傑出教學獎

中華醫事科技大學

第一作者

2015

104年科技部補助大專校院獎勵特殊優秀人才獎勵

科技部

第一作者

2014

103年國科會補助大專校院獎勵特殊優秀人才獎勵

國科會

第一作者

2013

102年中華醫事科技大學護理系百合花獎

中華醫事科技大學

第一作者

2013

102年國科會補助大專校院獎勵特殊優秀人才獎勵

國科會

第一作者

2011

100年國科會補助大專校院獎勵特殊優秀人才獎勵

國科會

第一作者

其他

英屬維京群島商勝浥國際股份有限公司研發總顧問

承洺科技有限公司研發諮詢顧問

中華民國新型專利(證書號碼: M514302,專利期限: 07/12/2025)

中華人民共和國新型專利(證書號碼: PE5567-CM專利期限: 11/06/2027)